Acne Vulgaris - What is it?



Acne vulgaris (sometimes called “acne”,  "pimples", "spots" or "zits") is a skin problem that happen when oil and dead skin cells clog up the pores. It can be in the form of comedones, papules, pustules, nodules, and/or cysts.

SYMPTOMPS

Acne mostly affects skin with a greater number of oil glands including the face, upper part of the chest, and back. and sometimes even more extensively over the body. 
Some people call acne as blackheads, blemishes, whiteheads, pimples, or zits. 

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CAUSES

PUBERTY

It most often affects adolescent, it is the most common skin disease in the world and affects the majority of the people at some point in life, mostly during puberty.  During puberty, androgen stimulate sebum production and unconrtolled proliferation of keratinocytes.
Acne is very common among teens. It usually gets better after the teenage years. Some women who never had acne growing up will have it as an adult, often right before their menstrual periods.
People may also be affected after puberty (though it becomes less common in adulthood), nearly half of people in their twenties and thirties continue to have acne.

HORMONE

Acne is often brought on by an increase in androgens such as testosterone. Its often involved excessive growth of the bacteria Propionibacterium acnes, which is normally present on the skin.

COSMETICS

Using oil-based skin products or cosmetics can make acne worse. Use skin products that don't clog your pores. They will say "noncomedogenic" on the label.

TYPES OF ACNE

Acne is classified by severity as mild, moderate, or severe, This type of categorization can be an important factor in determining the appropriate treatment regimen.
Mild acne is classically defined as open (blackheads) and closed limited to the face with occasional inflammatory lesion.
Moderate severity is when a higher number of inflammatory papules and pustules occur on the face compared to mild cases of acne and acne lesions also occur on the trunk of the body.
Severe acne can mean hundreds of pimples that can cover the face, neck, chest, and back. Or it can be bigger, solid, red lumps that are painful (cysts).
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DIAGNOSIS AND TREAMENT

Diagnosis is by examination, Examination in patients with acne vulgaris includes the following features:
  • Comedonal acne: Presence of open and closed comedones but no inflammatory (papules or nodules).Mild acne: Presence of comedones and a few papulopustule
  •  Moderate acne: Presence of comedones, inflammatory papules, and pustules; reater number of lesions  than in milde acne .
  • Nodulocystic acne: Presence of comedones, inflammatory lesions, and large nodules, scarring is often evident.       
Treatment, based on severity, can involve a variety of topical and systemic agents directed at reducing sebum production, comedone formation, inflammation, and bacterial counts and at normalizing keratinization. It also depends on the patient's age and sex, how long it has been present, and response to previous treatments.
  • Treatment for mild acne includes topical anti-acne preparations, lasers and lights
  • Treatment for moderate acne adds acne antibiotics such as tetracyclines and/or antiandrogens such as birth control pil. 
  • Treatment for severe acne may require a course of oral isotretinoin.

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PREVENTION

To help control acne, keep your skin clean. Avoid skin products that clog your pores. Wash your skin once or twice a day with a gentle soap or acne wash. Try not to scrub or pick at your pimples. This can make them worse and can cause scars.
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References:
https://en.wikipedia.org/wiki/Acne_vulgaris
http://emedicine.medscape.com/article/1069804-overview
http://www.merckmanuals.com/professional/dermatologic-disorders/acne-and-related-disorders/acne-vulgaris
http://www.webmd.com/skin-problems-and-treatments/acne/acne-vulgaris-topic-overview
http://www.dermnetnz.org/acne/acne-vulgaris.html

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